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Currently no one knows what causes MPS. The reason for the muscular pain may be reduced blood flow through the painful area, which restricts the muscles' ability to eliminate metabolic by-products, such as lactic acid. The resulting reduced oxygen flow combined with the body's failure to eliminate metabolic by-products would produce muscle knots, or "trigger points," as a result of direct inflammation of nerve endings. People suffering from MPS also seem to have altered pain perception and pain transmission compared to non-MPS sufferers.
Some factors that can cause the onset of MPS include:
- Sudden traumas involving musculoskeletal tissues.
- Damage to intervertebral discs.
- Nutritional deficiencies.
- Repetitive motions, intense physical activity, muscle strain due to over activity.
- Hormonal changes caused by menopause or pregnancy.
- Systemic conditions (gall bladder inflammation, heart attack).
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